ASCERT TRIAL

Problem 2 or 3VD
Format Retrospective multi-center
Treatment PCI or CABG
Control N/A
Population 189,793 patients
Inclusion criteria CABG or PCI with hospital discharge dates between January 1, 2004, and December 31, 2007

From sites participating in both the ACCF PCI database (CathPCI Registry) and the STS Adult Cardiac Surgery Database (ACD)
Exclusion criteria Single-vessel disease
Left main coronary artery disease
Cardiogenic shock within 24 hours before CABG or at the time of admission to the hospital for PCI
Myocardial infarction within 7 days before CABG or before admission to the hospital for PCI
Insertion of an intraaortic balloon pump before either procedure
CABG or valve surgery or PCI within 180 days before the current admission
Follow-up Median 2.67 years
Primary endpoint All-cause mortality
Secondary endpoint(s) -
Details .
Brief summary: Retrospective study showing CABG superior to PCI in 2-3VD at 4 years
PAPER: Comparative Effectiveness of Revascularization Strategies.
Date 2 Apr 2012
Journal N Engl J Med. 2012 Mar 27. [Epub ahead of print]
Information PCI vs. CABG in 2 or 3 vessel disease
-Huge retrospective study controlling for confounding

At 1 year
-No significant difference in ACM (RR 0.95)

At 4 years
-All-cause mortality lower for CABG (RR 0.79)